Identity & primary structure
Intact or subunit mass and peptide mapping selected for the construct and structural question.
Antibody & ADC Analytics
A scoped analytical package for antibody and ADC programs.
For mAbs, bispecifics, and ADC programs, APDK combines a defined core package with selected modules around the molecular format, program stage, sample context, and decision to be supported.
Best fit
Start with the molecule and the decision point.
- Monoclonal antibody programs
- Bispecific and other multispecific antibody formats
- Antibody-drug conjugate programs
- Projects requiring connected structural, physicochemical, functional, or impurity evidence
Core package
Establish identity, purity, size, charge, glycans, and PTMs.
The final method set is selected after sample and suitability review.
Purity, size & aggregation
SEC and CE-SDS used in an agreed package to address purity, size-related species, and aggregation questions.
Charge, glycans & PTMs
iCIEF or IEX and glycan analysis selected around heterogeneity and product-context questions.
Optional modules
Add only the evidence needed for the next decision.
Binding & potency
SPR/BLI, ELISA, or cell-based assays selected around intended function and the agreed question.
ADC conjugation questions
Conjugation-site mapping and agreed ADC structural questions linked to format and conjugation strategy.
Process-related impurities
Agreed residual targets defined from the process context, sample set, and intended use of the results.
Project inputs
Bring the context needed to confirm feasibility and sample requirements.
- Sequence, construct, antibody format, and conjugation strategy where applicable
- Sample form, available amount, handling history, and reference materials
- Program stage and the decision the package needs to support
- Known observations, comparison groups, controls, and prior method context
- Expected reporting format and technical review needs
Typical output
Receive a connected, review-ready analytical package.
- Scoped project plan agreed before work begins
- Attribute summary aligned to the approved scope
- Traceable figures and data tables
- Cross-method interpretation with stated evidence boundaries
Quality boundary
Method suitability and accreditation status are confirmed project by project.
Feasibility, sample requirements, controls, reporting format, and final deliverables are confirmed before project start. Accreditation applies only to activities within APDK’s current formal CNAS scope; method-specific applicability must be confirmed during project scoping.